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PI3K (phosphoinositide 3-kinase)

Showing 1 - 25 of >10,000
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Activated PI3K-delta Syndrome, Immunodeficiency Primary Trial in Shanghai (Rapamycin)

Recruiting
  • Activated PI3K-delta Syndrome
  • Immunodeficiency Primary
  • Shanghai, Shanghai, China
  • +1 more
Mar 21, 2022

Breast Cancer, ER-positive Breast Cancer, HER2-negative Breast Cancer Trial in Miami (AI+CDK4/6i, SERD+CDK4/6i, mTOR inhibitor +

Not yet recruiting
  • Breast Cancer
  • +3 more
  • Miami, Florida
    University of Miami
Apr 12, 2023

Colorectal Cancer, Gastric Cancer, HER2-negative Breast Cancer Trial (TOS-358)

Not yet recruiting
  • Colorectal Cancer
  • +8 more
  • (no location specified)
Jan 5, 2023

Healthy Trial in Nottingham ([14C]-Paxalisib Capsule)

Active, not recruiting
  • Healthy
  • [14C]-Paxalisib Capsule
  • Nottingham, United Kingdom
    Quotient Sciences
Aug 16, 2022

Estrogen Receptor-positive Breast Cancer, HER2-negative Breast Cancer, Invasive Ductal Breast Carcinoma Trial in Boston,

Active, not recruiting
  • Estrogen Receptor-positive Breast Cancer
  • +5 more
  • PI3K inhibitor BYL719
  • +3 more
  • Boston, Massachusetts
  • +1 more
Oct 14, 2022

Metastatic Breast Cancer Trial in East Melbourne (BYl719)

Completed
  • Metastatic Breast Cancer
  • East Melbourne, Victoria, Australia
    Peter MacCallum Cancer Centre
Aug 11, 2022

Endometrial Cancer, Ovarian Cancer Trial in Houston (Copanlisib, fulvestrant)

Recruiting
  • Endometrial Cancer
  • Ovarian Cancer
  • Houston, Texas
    M D Anderson Cancer Center
Sep 27, 2022

Cushing Disease Trial (Fimepinostat)

Not yet recruiting
  • Cushing Disease
  • (no location specified)
Jul 31, 2023

Solid Tumors, Adult, PIK3CA Mutation-Related Tumors, PIK3CA Mutation Trial in San Francisco (Alpelisib, Carboplatin,

Not yet recruiting
  • Solid Tumors, Adult
  • +7 more
  • San Francisco, California
    University of California, San Francisco
Jul 21, 2022

HR+, HER2-, Advanced Breast Cancer Trial (alpelisib)

Available
  • HR+, HER2-, Advanced Breast Cancer
  • (no location specified)
Jul 5, 2022

APDS Trial in Netherlands, United States (Leniolisib)

Not yet recruiting
  • APDS
  • Los Angeles, California
  • +4 more
Jan 12, 2023

Relapsed/Refractory Large Granular T Lymphocytic Leukemia Trial in Zhoukou, Tianjin (Linperlisib)

Not yet recruiting
  • Relapsed/Refractory Large Granular T Lymphocytic Leukemia
  • Zhoukou, Henan, China
  • +1 more
Dec 22, 2022

Autoimmune Hemolytic Anemia, Failure of Two Rounds of Treatment Trial in Zhoukou, Tianjin (Linperlisib)

Not yet recruiting
  • Autoimmune Hemolytic Anemia
  • Failure of Two Rounds of Treatment
  • Zhoukou, Henan, China
  • +1 more
Jan 7, 2023

APDS Trial in France, Netherlands, United States (Leniolisib)

Not yet recruiting
  • APDS
  • Los Angeles, California
  • +3 more
Jul 8, 2022

Advanced Solid Tumor Trial in Sutton, Manchester (SL-901)

Recruiting
  • Advanced Solid Tumor
  • Sutton, Surrey, United Kingdom
  • +1 more
May 16, 2022

Bile Acids in Acute Insulin Resistance

Recruiting
  • PI3K Gene Mutation
  • +4 more
  • Drug-induced acute insulin resistance due to PI3K inhibitor, AKT inhibitor, or mTOR inhibitor
  • New York, New York
    Columbia University Medical Center
Oct 6, 2022

Hyperglycemia Drug Induced Trial in Durham (REMD-477)

Terminated
  • Hyperglycemia Drug Induced
  • REMD-477
  • Durham, North Carolina
    Duke University Medical Center
Nov 4, 2022

Lung Cancer Squamous Cell, Solid Tumors, Head & Neck Cancer Trial in Boston (Palbociclib, Gedatolisib)

Recruiting
  • Lung Cancer Squamous Cell
  • +3 more
  • Boston, Massachusetts
  • +2 more
Jan 9, 2023

Estrogen Receptor-positive Breast Cancer Trial in Nashville (2-Week Ketogenic Diet, Letrozole)

Recruiting
  • Estrogen Receptor-positive Breast Cancer
  • Nashville, Tennessee
    Vanderbilt-Ingram Cancer Center
Sep 20, 2022

Locally Advanced Malignant Solid Tumor, Metastatic Malignant Tumor in the Bone, Metastatic Malignant Solid Tumor Trial

Withdrawn
  • Locally Advanced Malignant Solid Neoplasm
  • +3 more
  • (no location specified)
May 24, 2022

Activated PI3Kdelta Syndrome (APDS); PASLI Disease Trial in Worldwide (CDZ173)

Active, not recruiting
  • Activated PI3Kdelta Syndrome (APDS); PASLI Disease
  • Bethesda, Maryland
  • +7 more
Jul 22, 2022

MALT, Nodal Marginal Zone B-cell Lymphoma, Recurrent Grade 1 Follicular Lymphoma Trial in Atlanta, Columbus (drug, biological,

Completed
  • Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue
  • +8 more
  • PI3K inhibitor BKM120
  • +3 more
  • Atlanta, Georgia
  • +1 more
Jun 27, 2022

Alzheimer Trial in Hialeah, Maitland, Winter Park ([18F]PI-2620)

Recruiting
  • Alzheimer Disease
  • Hialeah, Florida
  • +2 more
Jan 18, 2023

Leukemia, Acute Lymphocytic Trial in Durham (Copanlisib)

Recruiting
  • Leukemia, Acute Lymphocytic
  • Durham, North Carolina
    Duke Cancer Center
Jun 28, 2022

Metastatic Breast Cancer, Advanced Breast Cancer, HR-positive Breast Cancer Trial (OP-1250, Ribociclib, Alpelisib)

Not yet recruiting
  • Metastatic Breast Cancer
  • +3 more
  • (no location specified)
Aug 18, 2022